A reason big enough to form a team; a mission, task, goal, problem,
or cause worth spending time, resources, and effort on

For our light affliction, which is but for a moment, worketh for us a far more exceeding and eternal weight of glory; While we look not at the things which are seen, but at the things which are not seen: for the things which are seen are temporal; but the things which are not seen are eternal.
2 Corinthians 4:17–18